Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

Guimond SE, Mycroft-West CJ, Gandhi NS, Tree JA, Buttigieg KR, Coombes N, Elmore MJ, Nyström K, Said J, Setoh YX, Amarilla AA, Modhiran N, Sng JDJ, Chhabra M, Watterson D, Young PR, Khromykh AA, Lima MA, A.Yates E, Karlsson R, Chen YH, Zhang Y, Hammond E, Dredge K, Carroll MW, Trybala E, Bergström T, Ferro V, Skidmore MA, Turnbull JE

bioRxiv - (-) - [2020-06-24; online 2020-06-24]

Category: Biochemistry

Category: Drug Discovery

Type: Preprint

DOI 10.1101/2020.06.24.169334

Crossref 10.1101/2020.06.24.169334


Publications 7.1.2