The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China.
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Gao J, Liu JQ, Wen HJ, Liu H, Hu WD, Han X, Li CX, Wang XJ
Respir Res 21 (1) 96 [2020-04-22; online 2020-04-22]
The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid detection had been considered as a criterion for ending antiviral treatment. We compared the two COVID-19 cases with similar backgrounds and CT image repeated intervals under treatment. Our report highlighted the unsynchronized expression in the changes of CT image and nucleic acid detection in COVID-19, and lasting positive nucleic acid test result in patients recovered from pneumonia. It may be contributed to recognize the disease and improve prevention.
PubMed 32321530
DOI 10.1186/s12931-020-01363-7
Crossref 10.1186/s12931-020-01363-7
NA: Provided in the article: CT images for 2 patients over 12 days