Bălăeţ M, Zadel A, Lingford-Hughes A, Paterson LM, Chamberlain SR, Trender W, Hellyer PJ, Hampshire A
Compr Psychiatry 140 (-) 152598
[2025-07-00; online 2025-04-15]
Changes in drug use in the general population during the COVID-19 pandemic and their long-term consequences are not well understood. We employed natural language processing and machine learning to analyse a large dataset of self-reported rates of and reasons for drug use during the pandemic, along with their associations with anxiety, depression and substance use problems post-pandemic. Our findings revealed a transient decrease in drug use at the pandemic's peak, primarily attributed to reduced social opportunities. Conversely, some participants reported increased drug use for self-medication, boredom, and lifestyle disruptions. While users of psychedelics and MDMA had anxiety and depression rates similar to non-users, users of opioid agonists and depressants-representing one in ten active drug users-reported greater mental health challenges post-pandemic. These results suggest that a subset of active drug users with distinct profiles faces elevated risks, particularly for anxiety and depression, and may benefit from targeted support.
Category: Social Science & Humanities
PubMed 40250155
DOI 10.1016/j.comppsych.2025.152598
Crossref 10.1016/j.comppsych.2025.152598
pii: S0010-440X(25)00025-2