COVID-19 in a patient with Good's syndrome and in 13 patients with common variable immunodeficiency.

Lindahl H, Smith CIE, Bergman P

Clin Immunol Commun 1 (-) 20-24 [2021-12-00; online 2021-10-08]

Antibody deficiencies constitute the majority of primary immunodeficiencies in adults. These patients have a well-established increased risk of bacterial infections but there is a lack of knowledge regarding the relative risks upon contracting COVID-19. In this monocentric study the disease course of COVID-19 in 1 patient with Good's syndrome and in 13 patients with common variable immunodeficiency (CVID) is described. The severity of disease ranged from very mild to severe. Several patients required hospitalization and immunomodulatory treatment but all survived. Although viral infections are not a typical feature of humoral immunodeficiencies we recommend that vigilance is increased in the management of patients with Good's syndrome and CVID during the COVID-19 pandemic.

Category: Health

Category: Other

Category: Serology

Type: Journal article

PubMed 38620775

DOI 10.1016/j.clicom.2021.08.003

Crossref 10.1016/j.clicom.2021.08.003

pmc: PMC8497938
pii: S2772-6134(21)00005-6


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