High seroconversion rate after vaccination with mRNA BNT162b2 vaccine against SARS-CoV-2 among people with HIV - but HIV viremia matters?
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Xu X, Vesterbacka J, Aleman S, Nowak P, COVAXID Study Group
AIDS 36 (3) 479-481 [2022-03-01; online 2022-01-28]
Our clinical trial of SARS-COV-2 mRNA vaccine in 90 HIV-infected persons on antiviral treatment demonstrated high seroconversion rate and high levels of spike IgG antibodies after two doses of vaccine. The vaccine was well tolerated and not associated with HIV RNA blips. However, the levels of spike IgG antibodies were lower in HIV patients than in healthy controls, especially among those with HIV RNA more than 50 copies/ml at baseline.
PubMed 35084386
DOI 10.1097/QAD.0000000000003135
Crossref 10.1097/QAD.0000000000003135
pii: 00002030-202203010-00018