Impact of the 2023/24 autumn-winter COVID-19 seasonal booster campaign in preventing severe COVID-19 cases in Italy (October 2023-March 2024).

Fotakis EA, Picasso E, Sacco C, Petrone D, Del Manso M, Bella A, Riccardo F, Odone A, Cannone A, Tallon M, De Angelis L, Sciurti A, Cescutti D, Pezzotti P, Fabiani M, Mateo-Urdiales A, Italian Integrated Surveillance of COVID-19 study group and of the Italian COVID-19 Vaccines Registry group

Vaccine 42 (26) 126375 [2024-09-18; online 2024-09-18]

We assessed the impact of the 2023/2024 COVID-19 vaccination campaign in Italy by estimating the number of averted COVID-19 severe cases (i.e. COVID-19 associated hospitalisations or deaths) between October 2023 and March 2024, in those aged ≥60 years. We estimated that 565 (95 % CI: 497-625) cases, corresponding to 2.1 % (95 % CI: 1.8-2.3) of the expected cases without a vaccination campaign, were averted. We simulated three vaccination coverage scenarios: 50 %, 75 %, 90 % (versus the observed 10.7 %), finding that 9.7 % (95 % CI: 8.5-10.7); 14.5 % (95 % CI: 12.8-16.1); and 17.4 % (95 % CI: 15.3-19.3) of the expected cases would have been averted, respectively.

PubMed 39298999

DOI 10.1016/j.vaccine.2024.126375

Crossref 10.1016/j.vaccine.2024.126375

pii: S0264-410X(24)01057-0