Two complementary model-based methods for calculating the risk of international spreading of a novel virus from the outbreak epicentre. The case of COVID-19.
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Massad E, Amaku M, Wilder-Smith A, Costa Dos Santos PC, Struchiner CJ, Coutinho FAB
Epidemiol Infect 148 (-) e109 [2020-06-09; online 2020-06-09]
We present two complementary model-based methods for calculating the risk of international spread of the novel coronavirus SARS-CoV-2 from the outbreak epicentre. One model aims to calculate the number of cases that would be exported from an endemic country to disease-free regions by travellers. The second model calculates the probability that an infected traveller will generate at least one secondary autochthonous case in the visited country. Although this paper focuses on the data from China, our methods can be adapted to calculate the risk of importation and subsequent outbreaks. We found an average R0 = 5.31 (ranging from 4.08 to 7.91) and a risk of spreading of 0.75 latent individuals per 1000 travellers. In addition, one infective traveller would be able to generate at least one secondary autochthonous case in the visited country with a probability of 23%.
PubMed 32513345
DOI 10.1017/S0950268820001223
Crossref 10.1017/S0950268820001223
pii: S0950268820001223
pmc: PMC7298081