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Acta Anaesthesiol Scand 65 (5) 576-577 [2021-05-00; online 2021-03-06]
Nitric oxide (NO) for inhalation has been a clinical option in the ICU since the early 1990s. Much has been written and claimed after the initial enthusiasm over an acutely improved arterial oxygenation in adult patients with ARDS. A few years ago, a meta-analysis (1) concluded that the regular use of inhaled NO (iNO) in patients with ARDS outside a clinical trial could not be recommended, as no benefit such as reduced mortality or time on the ventilator could be identified in published randomized studies.
PubMed 33533477
DOI 10.1111/aas.13788
Crossref 10.1111/aas.13788