Nitric oxide and COVID‐19: Dose, timing and how to administer it might be crucial

Frostell CG, Hedenstierna G

Acta Anaesthesiol Scand 65 (5) 576-577 [2021-05-00; online 2021-03-06]

Nitric oxide (NO) for inhalation has been a clinical option in the ICU since the early 1990s. Much has been written and claimed after the initial enthusiasm over an acutely improved arterial oxygenation in adult patients with ARDS. A few years ago, a meta-analysis (1) concluded that the regular use of inhaled NO (iNO) in patients with ARDS outside a clinical trial could not be recommended, as no benefit such as reduced mortality or time on the ventilator could be identified in published randomized studies.

Category: Health

Type: Other

PubMed 33533477

DOI 10.1111/aas.13788

Crossref 10.1111/aas.13788

Publications 9.5.0