Guallar MP, Meiriño R, Donat-Vargas C, Corral O, Jouvé N, Soriano V
Int J Infect Dis 97 (-) 290-292 [2020-08-00; online 2020-06-14]
A relationship between the infecting dose and the risk of disease severity has not been demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that were potentially exposed to distinct inoculum in Madrid. Overall each group developed divergent clinical forms of COVID-19. Our data support that a greater viral inoculum at the time of SARS-CoV-2 exposure might determine a higher risk of severe COVID-19.