The effect of COVID-19 vaccination on the risk of persistent post COVID-19 condition: Cohort study.
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Hedberg P, van der Werff SD, Nauclér P
The Journal of Infectious Diseases - (-) -
[2025-03-12; online 2025-03-12]
We conducted a population-based cohort study in Stockholm, Sweden, to investigate the effect of COVID-19 vaccination on the risk of developing persistent PCC in individuals surviving the first year after a SARS-CoV-2 infection. 331,042 individuals were included, of which 852 had persistent PCC. The adjusted RR (95% CI) for developing persistent PCC compared with unvaccinated individuals was 0.81 (0.59-1.10) for 1 dose, 0.42 (0.35-0.52) for 2 doses, and 0.37 (0.27-0.52) for three doses. Reduced risks for vaccinated individuals were also observed when restricting the analyses to pre-Omicron and Omicron, as well as all subgroups including sex, age, and previous infection.
PubMed 40071640
DOI 10.1093/infdis/jiaf133
Crossref 10.1093/infdis/jiaf133
pii: 8071565