Funder: H2020

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Year 2023

PubMed DOI Crossref
Microneedle Patch for Painless Intradermal Collection of Interstitial Fluid Enabling Multianalyte Measurement of Small Molecules, SARS-CoV-2 Antibodies, and Protein Profiling.
Ribet F, Bendes A, Fredolini C, ..., Stemme G, Roxhed N
Adv Healthc Mater 12 (13) e2202564 [2023-05-00; online 2023-02-21]
Category: Biochemistry Category: Health Funder: H2020 Type: Journal article
PubMed DOI Crossref
SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses.
Christensen D, Polacek C, Sheward DJ, ..., Bukh J, Pedersen GK
Front Immunol 14 (-) 941281 [2023-01-23; online 2023-01-23]
Category: Biochemistry Category: Health Funder: H2020 Type: Journal article

Year 2022

PubMed DOI Crossref
Mucosal IgA against SARS-CoV-2 Omicron Infection. Reply.
Åberg M, Smed-Sörensen A, Thålin C
N Engl J Med 387 (21) e55 [2022-11-24; online 2022-11-24]
Category: Biochemistry Category: Health Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Biobanks for COVID-19 research Type: Journal article
PubMed DOI Crossref
Protection against SARS-CoV-2 transmission by a parenteral prime-Intranasal boost vaccine strategy.
Christensen D, Polacek C, Sheward DJ, ..., Bukh J, Pedersen GK
EBioMedicine - (-) 104248 [2022-09-05; online 2022-09-05]
Category: Biochemistry Category: Health Funder: H2020 Type: Journal article
PubMed DOI Crossref
Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies.
Hanke L, Sheward DJ, Pankow A, ..., McInerney GM, Murrell B
Sci Adv 8 (12) eabm0220 [2022-03-25; online 2022-03-25]
Category: Biochemistry Category: Health Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.
Hanke L, Das H, Sheward DJ, ..., Murrell B, McInerney GM
Nat Commun 13 (1) 155 [2022-01-10; online 2022-01-10]
Category: Biochemistry Category: Health Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Drug discovery and repurposing of drugs Type: Journal article

Year 2021

PubMed DOI Crossref
Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models.
Sheward DJ, Mandolesi M, Urgard E, ..., Karlsson Hedestam GB, Murrell B
Cell Rep Med 2 (11) 100450 [2021-11-16; online 2021-10-23]
Category: Biochemistry Category: Genomics & transcriptomics Category: Health Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
Infection of Brain Pericytes Underlying Neuropathology of COVID-19 Patients.
Bocci M, Oudenaarden C, Sàenz-Sardà X, ..., Englund E, Pietras K
Int J Mol Sci 22 (21) 11622 [2021-10-27; online 2021-10-27]
Category: Health Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Biobanks for COVID-19 research Type: Journal article
PubMed DOI Crossref
SARS-CoV-2 specific B- and T-cell immunity in a population-based study of young Swedish adults.
Björkander S, Du L, Zuo F, ..., Pan-Hammarström Q, BAMSE COVID-19 Study Group
J Allergy Clin Immunol - (-) - [2021-10-22; online 2021-10-22]
Category: Biochemistry Category: Health Funder: H2020 Funder: Hjärt-Lungfonden Funder: VR Type: Journal article
DOI Crossref
Antigen receptor stimulation drives selection against pathogenic mtDNA variants that dysregulate lymphocyte responses
Zhang J, Koolmeister C, Han J, ..., Dopico XC, Rorbach J
- - (-) - [2021-10-07; online 2021-10-07]
Category: Biochemistry Category: Health Funder: H2020 Funder: VR Type: Preprint
PubMed DOI Crossref
A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies.
Mravinacova S, Jönsson M, Christ W, ..., Månberg A, Hober S
N Biotechnol 66 (-) 46-52 [2021-10-07; online 2021-10-07]
Category: Biochemistry Category: Health Funder: H2020 Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out.
Soares RRG, Akhtar AS, Pinto IF, ..., Pelechano V, Russom A
Lab Chip 21 (15) 2932-2944 [2021-08-07; online 2021-06-11]
Category: Other Funder: H2020 Funder: KAW/SciLifeLab Research Area: Diagnostics for virus Type: Journal article
PubMed DOI Crossref
Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease.
Ricke-Hoch M, Stelling E, Lasswitz L, ..., Haverich A, Hilfiker-Kleiner D
PLoS One 16 (8) e0255335 [2021-08-04; online 2021-08-04]
Category: Biochemistry Category: Health Funder: H2020 Type: Journal article
PubMed DOI Crossref
Persisting Salivary IgG Against SARS-CoV-2 at 9 Months After Mild COVID-19: A Complementary Approach to Population Surveys.
Alkharaan H, Bayati S, Hellström C, ..., Pin E, Sällberg Chen M
The Journal of Infectious Diseases 224 (3) 407-414 [2021-08-02; online 2021-05-13]
Category: Health Funder: H2020 Funder: KAW/SciLifeLab Research Area: High-throughput and high-content serology Type: Journal article
PubMed DOI Crossref
A phenomics approach for antiviral drug discovery.
Rietdijk J, Tampere M, Pettke A, ..., Puumalainen MR, Carreras-Puigvert J
BMC Biol 19 (1) 156 [2021-08-02; online 2021-08-02]
Category: Biochemistry Category: Drug Discovery Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Drug discovery and repurposing of drugs Type: Journal article
PubMed DOI Crossref
Natural killer cells and unconventional T cells in COVID-19
Björkström NK, Ponzetta A
Current Opinion in Virology 49 (-) 176-182 [2021-08-00; online 2021-08-00]
Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Type: Review
PubMed DOI Crossref
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.
Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM
Nat Commun 12 (1) 3695 [2021-06-17; online 2021-06-17]
Category: Health Category: Serology Funder: H2020 Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Natural killer cells in antiviral immunity.
Björkström NK, Strunz B, Ljunggren H
Nat Rev Immunol - (-) - [2021-06-11; online 2021-06-11]
Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Type: Review
PubMed DOI Crossref
Impact of COVID-19 pandemic on mental health and health behaviors in Swedish adolescents.
Chen Y, Osika W, Henriksson G, Dahlstrand J, Friberg P
Scand J Public Health - (-) 14034948211021724 [2021-06-08; online 2021-06-08]
Category: Public Health Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
SARS-CoV-2 in hospital indoor environments is predominantly non-infectious.
Krambrich J, Akaberi D, Ling J, ..., Hagbom M, Lundkvist Å
Virol J 18 (1) 109 [2021-06-02; online 2021-06-02]
Category: Biochemistry Category: Health Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: High-throughput and high-content serology Type: Journal article
PubMed DOI Crossref
Evaluation of Production Lots of a Rapid Point-of-Care Lateral Flow Serological Test Intended for Identification of IgM and IgG against the N-Terminal Part of the Spike Protein (S1) of SARS-CoV-2.
Hoffman T, Kolstad L, Rönnberg B, Lundkvist Å
Viruses 13 (6) - [2021-05-31; online 2021-05-31]
Category: Biochemistry Category: Health Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: High-throughput and high-content serology Type: Journal article
PubMed DOI Crossref
Diagnostic Potential of a Luminex-Based Coronavirus Disease 2019 Suspension Immunoassay (COVID-19 SIA) for the Detection of Antibodies against SARS-CoV-2.
Hoffman T, Kolstad L, Lindahl JF, ..., Rönnberg B, Lundkvist Å
Viruses 13 (6) - [2021-05-26; online 2021-05-26]
Category: Biochemistry Category: Other Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: High-throughput and high-content serology Type: Journal article
PubMed DOI Crossref
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
De Gasparo R, Pedotti M, Simonelli L, ..., Ruzek D, Varani L
Nature 593 (7859) 424-428 [2021-05-20; online 2021-03-25]
Category: Biochemistry Category: Health Funder: H2020 Type: Journal article
PubMed DOI Crossref
Antiviral Activity of Silver, Copper Oxide and Zinc Oxide Nanoparticle Coatings against SARS-CoV-2.
Merkl P, Long S, McInerney GM, Sotiriou GA
Nanomaterials (Basel) 11 (5) - [2021-05-17; online 2021-05-17]
Category: Biochemistry Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses.
Mandolesi M, Sheward DJ, Hanke L, ..., Karlsson Hedestam GB, Murrell B
Cell Rep Med 2 (4) 100252 [2021-04-20; online 2021-04-05]
Category: Biochemistry Category: Health Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
Cell type resolved quantitative proteomics map of interferon response against SARS-CoV-2.
Saccon E, Chen X, Mikaeloff F, ..., Neogi U, Gupta S
iScience 24 (5) 102420 [2021-04-20; online 2021-04-20]
Category: Biochemistry Funder: H2020 Funder: VR Type: Journal article
DOI Crossref
Driving potent neutralization of a SARS-CoV-2 Variant of Concern with a heterotypic boost
Sheward DJ, Mandolesi M, Kim C, ..., Hedestam GBK, Murrell B
bioRxiv - (-) - [2021-04-05; online 2021-04-05]
Category: Biochemistry Category: Genomics & transcriptomics Funder: H2020 Funder: VR Type: Preprint
PubMed DOI Crossref
Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum.
Lehto J, Huguet Ninou A, Chioureas D, Jonkers J, Gustafsson NMS
Cancers (Basel) 13 (6) - [2021-03-22; online 2021-03-22]
Category: Drug Discovery Category: Health Funder: H2020 Type: Journal article
PubMed DOI Crossref
Anti-SARS-CoV2 antibody responses in serum and cerebrospinal fluid of COVID-19 patients with neurological symptoms
Cunningham JL, Virhammar J, Rönnberg B, ..., Karlsson Hedestam GB, Rostami E
The Journal of Infectious Diseases - (-) - [2021-03-21; online 2021-03-21]
Category: Biochemistry Category: Health Category: Proteins Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: High-throughput and high-content serology Type: Journal article
PubMed DOI Crossref
Indoor Model Simulation for COVID-19 Transport and Exposure.
Hussein T, Löndahl J, Thuresson S, ..., Mahura A, Kulmala M
Int J Environ Res Public Health 18 (6) - [2021-03-12; online 2021-03-12]
Category: Other Category: Public Health Funder: H2020 Funder: Hjärt-Lungfonden Type: Journal article
DOI Crossref
The emergence and ongoing convergent evolution of the N501Y lineages coincides with a major global shift in the SARS-CoV-2 selective landscape
Martin DP, Weaver S, Tegally H, ..., None , None
medRxiv - (-) - [2021-03-05; online 2021-03-05]
Category: Genomics & transcriptomics Funder: H2020 Type: Preprint
PubMed DOI Crossref
Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection.
Manisty C, Treibel TA, Jensen M, ..., Noursadeghi M, Moon JC
EBioMedicine 65 (-) 103259 [2021-03-01; online 2021-03-01]
Category: Genomics & transcriptomics Category: Proteins Funder: H2020 Type: Journal article
PubMed DOI Crossref
Promoting Mental Health and Well-Being among Adolescent Young Carers in Europe: A Randomized Controlled Trial Protocol.
Casu G, Hlebec V, Boccaletti L, ..., Manattini A, Hanson E
Int J Environ Res Public Health 18 (4) - [2021-02-19; online 2021-02-19]
Category: Public Health Funder: H2020 Type: Journal article
DOI Crossref
Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2
Ehling RA, Weber CR, Mason DM, ..., Rudolf F, Reddy ST
bioRxiv - (-) - [2021-02-12; online 2021-02-12]
Category: Biochemistry Funder: H2020 Type: Preprint
PubMed DOI Crossref
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Koenig PA, Das H, Liu H, ..., Wu NC, Schmidt FI
Science 371 (6530) eabe6230 [2021-01-12; online 2021-01-12]
Category: Biochemistry Category: Imaging Category: Proteins Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.
Monteil V, Dyczynski M, Lauschke VM, ..., Penninger JM, Mirazimi A
EMBO Mol Med 13 (1) e13426 [2021-01-11; online 2020-12-14]
Category: Biochemistry Category: Drug Discovery Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice.
Wørzner K, Sheward DJ, Schmidt ST, ..., Christensen D, Pedersen GK
EBioMedicine 63 (-) 103197 [2021-01-00; online 2021-01-07]
Category: Biochemistry Category: Drug Discovery Funder: H2020 Research Area: Data-driven research – models and AI Type: Journal article

Year 2020

PubMed DOI Crossref
Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids.
Pettke A, Tampere M, Pronk R, ..., Mirazimi A, Puumalainen MR
Viruses 13 (1) 37 [2020-12-29; online 2020-12-29]
Category: Biochemistry Funder: H2020 Funder: VR Type: Journal article
DOI Crossref
Seropositivity in blood donors and pregnant women during 9-months of SARS-CoV-2 transmission in Stockholm, Sweden
Dopico XC, Muschiol S, Christian M, ..., Albert J, Karlsson Hedestam GB
medRxiv - (-) - [2020-12-26; online 2020-12-26]
Category: Health Category: Serology Funder: H2020 Funder: VR Type: Preprint
PubMed DOI Crossref
Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs.
Moliner-Morro A, J Sheward D, Karl V, ..., McInerney GM, Hanke L
Biomolecules 10 (12) - [2020-12-11; online 2020-12-11]
Category: Biochemistry Category: Proteins Funder: H2020 Funder: VR Funder: VR: Special COVID-19 funding Type: Journal article
PubMed DOI Crossref
Mechanisms of a Sustained Anti‐inflammatory Drug Response in Alveolar Macrophages Unraveled with Mathematical Modeling
Nyman E, Lindh M, Lövfors W, ..., Fridén M, Cedersund G
CPT Pharmacometrics Syst. Pharmacol. 9 (12) 707-717 [2020-12-00; online 2020-12-13]
Category: Biochemistry Category: Other Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Data-driven research – models and AI Type: Journal article
DOI Crossref
Global analysis of more than 50,000 SARS-CoV-2 genomes reveals epistasis between eight viral genes
Zeng HL, Dichio V, Rodríguez Horta E, Thorell K, Aurell E
Proc Natl Acad Sci USA - (-) 202012331 [2020-11-17; online 2020-11-17]
Category: Genomics & transcriptomics Funder: H2020 Type: Journal article
PubMed DOI Crossref
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Custódio TF, Das H, Sheward DJ, ..., Hällberg BM, Löw C
Nat Commun 11 (1) - [2020-11-04; online 2020-11-04]
Category: Biochemistry Category: Other Category: Proteins Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study.
Gill D, Arvanitis M, Carter P, ..., Sin DD, Burgess S
R Soc Open Sci 7 (11) 200958 [2020-11-00; online 2020-11-18]
Category: Biochemistry Category: Health Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden.
Rudberg AS, Havervall S, Månberg A, ..., Hober S, Thålin C
Nat Commun 11 (1) 5064 [2020-10-08; online 2020-10-08]
Category: Health Category: Serology Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Biobanks for COVID-19 research Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.
Hanke L, Vidakovics Perez L, Sheward DJ, ..., Murrell B, McInerney GM
Nat Commun 11 (1) 4420 [2020-09-04; online 2020-09-04]
Category: Biochemistry Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2.
Sauvat A, Ciccosanti F, Colavita F, ..., Piacentini M, Kroemer G
Cell Death Dis 11 (8) 656 [2020-08-19; online 2020-08-19]
Category: Biochemistry Category: Drug Discovery Funder: H2020 Type: Journal article
DOI Crossref
Discriminative Bayesian Serology: Counting Without Cutoffs
Christian M, Murrell B
bioRxiv - (-) - [2020-07-14; online 2020-07-14]
Category: Other Category: Serology Funder: H2020 Type: Preprint
PubMed DOI Crossref
Development of passive immunity against SARS-CoV-2 for management of immunodeficient patients-a perspective.
Hammarström L, Abolhassani H, Baldanti F, Marcotte H, Pan-Hammarström Q
J Allergy Clin Immunol 146 (1) 58-60 [2020-07-00; online 2020-05-12]
Category: Health Funder: H2020 Funder: VR Type: Journal article
PubMed DOI Crossref
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.
Monteil V, Kwon H, Prado P, ..., Mirazimi A, Penninger JM
Cell 181 (4) 905-913.e7 [2020-05-14; online 2020-04-24]
Category: Biochemistry Category: Health Funder: H2020 Funder: VR Type: Journal article
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