Category: Proteins

Increased cerebrospinal fluid ACE2 fragments as a read-out of brain infection in COVID-19 encephalopathy patients.

Lennol MP, García-Ayllón M, Avilés-Granados C, ..., Pilotto A, Sáez-Valero J

The Journal of Infectious Diseases - (-) - [2025-02-26; online 2025-02-26] Open Access

Category: Health Category: Proteins Funder: VR Type: Journal article

Structural prediction of chimeric immunogen candidates to elicit targeted antibodies against betacoronaviruses.

Simpson J, Kasson PM

PLoS Comput Biol 21 (2) e1012812 [2025-02-00; online 2025-02-05] Open Access

Category: Genomics & transcriptomics Category: Proteins Type: Journal article

Molecular mechanisms behind the anti corona virus activity of small metal oxide nanoparticles.

Greijer B, Nefedova A, Agback T, ..., Ivask A, Kessler VG

Nanoscale - (-) - [2025-01-23; online 2025-01-23] Open Access

Category: Biochemistry Category: Proteins Funder: VR Type: Journal article

High prevalence of undocumented SARS-CoV-2 infections revealed by analysis of nucleocapsid-specific IgG responses in diagnosed and undiagnosed individuals.

Blom K, Galanis I, Bacchus P, ..., Groenheit R, Klingström J

PLOS Glob Public Health 5 (1) e0003300 [2025-01-22; online 2025-01-22] Open Access

Category: Proteins Category: Serology Funder: VR Type: Journal article

Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugase.

Ayala-Torres C, Liu J, Dantuma NP, Masucci MG

Autophagy - (-) 1-20 [2025-01-02; online 2025-01-02] Open Access

Category: Proteins Funder: KAW/SciLifeLab National COVID program

Oral Immunisation With Non-GMO Surface Displayed SARS-CoV-2 Spike Epitopes on Bacteria-Like Particles Provokes Robust Humoral and Cellular Immune Responses, and Modulated the Gut Microbiome in Mice.

Vasquez R, Song JH, Mendoza RM, ..., Valeriano VD, Kang D

Microb Biotechnol 18 (1) e70073 [2025-01-00; online 2025-01-11] Open Access

Category: Proteins Category: Vaccines Type: Journal article

Overlapping Systemic Proteins in COVID-19 and Lung Fibrosis Associated with Tissue Remodeling and Inflammation.

Svobodová B, Löfdahl A, Nybom A, ..., Westergren-Thorsson G, Elowsson L

Biomedicines 12 (12) - [2024-12-19; online 2024-12-19] Open Access

Category: Health Category: Post-COVID Category: Proteins Category: Serology Funder: Hjärt-Lungfonden Funder: VR Type: Journal article

Characterization of SARS-CoV-2 nucleocapsid protein oligomers.

Farci D, Graça AT, Hall M, ..., Schröder WP, Piano D

J Struct Biol 217 (1) 108162 [2024-12-13; online 2024-12-13] Open Access

Category: Genomics & transcriptomics Category: Imaging Category: Proteins Type: Journal article

SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs.

Long S, Guzyk M, Perez Vidakovics L, ..., Achour A, McInerney GM

Nat Commun 15 (1) 10607 [2024-12-05; online 2024-12-05] Open Access

Category: Genomics & transcriptomics Category: Proteins Type: Journal article

Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness.

Bilev E, Wild N, Momayyezi P, ..., Achour A, Hammer Q

PLoS Pathog 20 (12) e1012755 [2024-12-00; online 2024-12-09] Open Access

Category: Proteins Funder: VR Type: Journal article

Maternal infection of SARS-CoV-2 during the first and second trimesters leads to newborn telomere shortening.

Wang L, Zhang J, Liu F, ..., Kong F, Xu D

J Transl Med 22 (1) 1049 [2024-11-21; online 2024-11-21] Open Access

Category: Health Category: Proteins Category: Serology Type: Journal article

SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion.

Christ W, Kapell S, Sobkowiak MJ, ..., El Andaloussi S, Ezzat K

ACS Chem Neurosci 15 (22) 4095-4104 [2024-11-20; online 2024-11-07]

Avidity maturation of anti-spike IgG after vaccination in COVID-19 convalescent vs COVID-19 naïve patients.

Löfström E, Eringfält A, Kötz A, Tham J, Undén J

APMIS - (-) - [2024-11-07; online 2024-11-07] Open Access

Category: Proteins Category: Serology Type: Journal article

Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination.

Yalcinkaya A, Cavalli M, Aranda-Guillén M, ..., Hallberg P, Landegren N

Sci Rep 14 (1) 24512 [2024-10-18; online 2024-10-18] Open Access

Category: Proteins Category: Serology Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

Systemic increase in IL-26 is associated with severe COVID-19 and comorbid obstructive lung disease.

Cardenas EI, Robertson J, Misaghian S, ..., Gisslén M, Lindén A

Front Immunol 15 (-) 1434186 [2024-10-04; online 2024-10-04] Open Access

Category: Proteins Funder: Hjärt-Lungfonden Funder: KAW/SciLifeLab National COVID program Funder: VR

The CoV-Y domain of SARS-CoV-2 Nsp3 interacts with BRAP to stimulate NF-κB signaling and induce host inflammatory responses.

Wang K, Ni X, Deng X, ..., Zeng R, Lei J

Int J Biol Macromol 280 (Pt 4) 136123 [2024-09-28; online 2024-09-28]

Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation.

Huynh PNH, Khamplong P, Phan M, ..., Choowongkomon K, Vo CT

RSC Med Chem - (-) - [2024-09-03; online 2024-09-03]

Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families.

Vukovich MJ, Shiakolas AR, Lindenberger J, ..., Sautto GA, Georgiev IS

PLoS Pathog 20 (9) e1012499 [2024-09-00; online 2024-09-18] Open Access

Category: Genomics & transcriptomics Category: Proteins Funder: SciLifeLab PLP program Type: Journal article

The role of complement and extracellular vesicles in the development of pulmonary embolism in severe COVID-19 cases.

Dumitrescu G, Antovic J, Soutari N, ..., Rooyackers O, Taxiarchis A

PLoS One 19 (8) e0309112 [2024-08-23; online 2024-08-23] Open Access

Category: Proteins Category: Serology Funder: KAW/SciLifeLab National COVID program Type: Journal article

Defining short linear motif binding determinants by phage-based multiplexed deep mutational scanning

Benz C, Maasen L, Simonetti L, ..., Davey NE, Ivarsson Y

- - (-) - [2024-08-06; online 2024-08-06]

Category: Proteins Type: Preprint

Protective non-neutralizing SARS-CoV-2 monoclonal antibodies.

Izadi A, Nordenfelt P

Trends Immunol 45 (8) 609-624 [2024-08-00; online 2024-07-20] Open Access

Category: Proteins Funder: VR Type: Journal article

Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients.

Didriksson I, Lengquist M, Spångfors M, ..., Friberg H, Schiopu A

J Intensive Care 12 (1) 26 [2024-07-09; online 2024-07-09] Open Access

Category: Proteins Funder: Hjärt-Lungfonden Funder: VR Type: Journal article

Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mapping.

Thalén NB, Karlander M, Lundqvist M, ..., Ohlin M, Rockberg J

Commun Biol 7 (1) 805 [2024-07-03; online 2024-07-03] Open Access

Category: Imaging Category: Proteins Type: Journal article

ADAM-17 Activity and Its Relation to ACE2: Implications for Severe COVID-19.

Sun J, Edsfeldt A, Svensson J, ..., Goncalves I, Swärd P

Int J Mol Sci 25 (11) - [2024-05-29; online 2024-05-29] Open Access

Category: Genomics & transcriptomics Category: Proteins Funder: Hjärt-Lungfonden Funder: VR Type: Journal article

Yin and yang of interferons: lessons from the coronavirus disease 2019 (COVID-19) pandemic.

Svensson Akusjärvi S, Zanoni I

Curr Opin Immunol 87 (-) 102423 [2024-05-21; online 2024-05-21]

Category: Other Category: Proteins Funder: VR Type: Review

Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies.

Sheward DJ, Pushparaj P, Das H, ..., Karlsson Hedestam GB, Hällberg BM

Cell Rep Med - (-) 101577 [2024-05-15; online 2024-05-15]

Category: Genomics & transcriptomics Category: Omicron VoC Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

Anexelekto (AXL) no more: microRNA-155 (miR-155) controls the "Uncontrolled" in SARS-CoV-2.

Papadopoulos KI, Papadopoulou A, Aw TC

Hum Cell 37 (3) 582-592 [2024-05-00; online 2024-03-12]

Category: Genomics & transcriptomics Category: Proteins Type: Review

Proteome profiling of home-sampled dried blood spots reveals proteins of SARS-CoV-2 infections.

Fredolini C, Dodig-Crnković T, Bendes A, ..., Roxhed N, Schwenk JM

Commun Med (Lond) 4 (1) 55 [2024-04-02; online 2024-04-02] Open Access

Synthetic coevolution reveals adaptive mutational trajectories of neutralizing antibodies and SARS-CoV-2

Ehling RA, Minot M, Overath MD, ..., Murrell B, Reddy ST

- - (-) - [2024-04-01; online 2024-04-01]

Category: Proteins Category: Serology Type: Preprint

Plasma neutrophil gelatinase-associated lipocalin independently predicts dialysis need and mortality in critical COVID-19.

Engström J, Koozi H, Didriksson I, ..., Frigyesi A, Spångfors M

Sci Rep 14 (1) 6695 [2024-03-20; online 2024-03-20] Open Access

Category: Health Category: Proteins Type: Journal article

New insights into complex formation by SARS-CoV-2 nsp10 and nsp14.

Sele C, Krupinska E, Andersson Rasmussen A, ..., Fisher SZ, Knecht W

Nucleosides Nucleotides Nucleic Acids - (-) 1-15 [2024-02-29; online 2024-02-29]

Category: Genomics & transcriptomics Category: Proteins Type: Journal article

Identifying novel inhibitors targeting Exportin-1 for the potential treatment of COVID-19.

Sharma T, Mondal T, Khan S, ..., Baig MH, Dong J

Arch Microbiol 206 (2) 69 [2024-01-19; online 2024-01-19]

Category: Drug Discovery Category: Genomics & transcriptomics Category: Proteins Funder: VR Type: Journal article

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Altincekic N, Jores N, Löhr F, ..., Sreeramulu S, Schwalbe H

ACS Chem Biol - (-) - [2024-01-17; online 2024-01-17] Open Access

Category: Drug Discovery Category: Proteins Funder: H2020 Funder: KAW/SciLifeLab National COVID program Type: Journal article

Profiling of Surface Protein Epitopes on Viral Particles by Multiplex Dual-Reporter Strategy.

Sahi M, Andersson S, Mattson C, ..., Chiodi F, Fredolini C

J Vis Exp - (203) - [2024-01-12; online 2024-01-12]

Category: Proteins Funder: KAW/SciLifeLab National COVID program Type: Journal article

Immune system perturbations in patients with long COVID.

Rodriguez L, Brodin P

Trends Mol Med - (-) - [2024-01-04; online 2024-01-04]

Category: Post-COVID Category: Proteins Category: Serology Type: Journal article

Exploring the conformational dynamics of the SARS-CoV-2 SL4 hairpin by combining optical tweezers and base analogues.

Sundar Rajan V, Wypijewska Del Nogal A, Levin S, Wilhelmsson LM, Westerlund F

Nanoscale 16 (2) 752-764 [2024-01-03; online 2024-01-03]

Category: Biochemistry Category: Genomics & transcriptomics Category: Proteins Funder: VR Type: Journal article

The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.

Garvanska DH, Alvarado RE, Mundt FO, ..., Menachery VD, Nilsson J

EMBO Rep - (-) - [2024-01-02; online 2024-01-02] Open Access

Category: Proteins Funder: VR Type: Journal article

Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity.

Ghazal A, Clarke D, Abdel-Rahman MA, ..., Hijazi K, Houssen WE

Peptides 173 (-) 171139 [2023-12-22; online 2023-12-22]

Influenza-A mediated pre-existing immunity levels to SARS-CoV-2 could predict early COVID-19 outbreak dynamics.

Almazán NM, Rahbar A, Carlsson M, ..., Sörensen B, Söderberg-Nauclér C

iScience 26 (12) 108441 [2023-12-15; online 2023-11-14]

Category: Biochemistry Category: Health Category: Proteins Category: Serology Category: Vaccines Funder: H2020 Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

Dramatic Differences between the Structural Susceptibility of the S1 Pre- and S2 Postfusion States of the SARS-CoV-2 Spike Protein to External Electric Fields Revealed by Molecular Dynamics Simulations.

Lipskij A, Arbeitman C, Rojas P, Ojeda-May P, Garcia ME

Viruses 15 (12) - [2023-12-11; online 2023-12-11] Open Access

Category: Biochemistry Category: Proteins Type: Journal article

Polymethoxyflavone from Citrus depressa as an inhibitor against various variants of SARS-CoV-2 spike protein.

Liu T, Hsu S, Hsieh YSY, Liu H, Lee C

J Ethnopharmacol 320 (-) 117412 [2023-11-21; online 2023-11-21]

Category: Biochemistry Category: Drug Discovery Category: Proteins Type: Journal article

Development of a proteomic signature associated with severe disease for patients with COVID-19 using data from 5 multicenter, randomized, controlled, and prospective studies.

Castro-Pearson S, Samorodnitsky S, Yang K, ..., Safo SE, Tignanelli CJ

Sci Rep 13 (1) 20315 [2023-11-20; online 2023-11-20]

Design, structure and plasma binding of ancestral β-CoV scaffold antigens.

Hueting D, Schriever K, Sun R, ..., Andréll J, Syrén P

Nat Commun 14 (1) 6527 [2023-10-16; online 2023-10-16] Open Access

Category: Biochemistry Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).

Proal AD, VanElzakker MB, Aleman S, ..., Yonker LM, Wherry EJ

Nat Immunol 24 (10) 1616-1627 [2023-10-00; online 2023-09-04]

Category: Biochemistry Category: Post-COVID Category: Proteins Type: Review

Evaluation of a human mucosal tissue explant model for SARS-CoV-2 replication.

Gordhan BG, Herrera C, Pillay A, ..., Fox J, Kana BD

PLoS One 18 (9) e0291146 [2023-09-28; online 2023-09-28]

Category: Genomics & transcriptomics Category: Health Category: Other Category: Proteins Type: Journal article

Prevalence of SARS-CoV-2 Omicron Sublineages and Spike Protein Mutations Conferring Resistance against Monoclonal Antibodies in a Swedish Cohort during 2022-2023.

Haars J, Palanisamy N, Wallin F, ..., Kaden R, Lennerstrand J

Microorganisms 11 (10) - [2023-09-27; online 2023-09-27] Open Access

Category: Biochemistry Category: Proteins Type: Journal article

De novo design of anti-variant COVID-19 vaccine.

Goswami A, Kumar M, Ullah S, Gore MM

Biol Methods Protoc 8 (1) bpad021 [2023-09-26; online 2023-09-26]

Category: Proteins Category: Vaccines Type: Journal article

Comprehensive proteomics and meta-analysis of COVID-19 host response.

Babačić H, Christ W, Araújo JE, ..., Klingström J, Pernemalm M

Nat Commun 14 (1) 5921 [2023-09-22; online 2023-09-22]

Category: Other Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

Mihalič F, Benz C, Kassa E, ..., Jemth P, Ivarsson Y

Nat Commun 14 (1) 5636 [2023-09-13; online 2023-09-13] Open Access

Category: Biochemistry Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

Oligomeric State of β-Coronavirus Non-Structural Protein 10 Stimulators Studied by Small Angle X-ray Scattering.

Knecht W, Fisher SZ, Lou J, ..., Pinotsis N, Kozielski F

Int J Mol Sci 24 (17) - [2023-09-04; online 2023-09-04]

Category: Imaging Category: Proteins Type: Journal article

Pentameric C-reactive protein is a better prognostic biomarker and remains elevated for longer than monomeric CRP in hospitalized patients with COVID-19.

Hopkins FR, Nordgren J, Fernandez-Botran R, ..., Sjöwall J, Larsson M

Front Immunol 14 (-) 1259005 [2023-09-01; online 2023-09-01]

Category: Biochemistry Category: Health Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner.

Correa Y, Del Giudice R, Waldie S, ..., Roosen-Runge F, Cárdenas M

J Colloid Interface Sci 645 (-) 627-638 [2023-09-00; online 2023-04-29]

Category: Biochemistry Category: Proteins Funder: VR Type: Journal article

Entangling of Peptide Nanofibers Reduces the Invasiveness of SARS-CoV-2.

Yang P, Ye X, Liu M, ..., Wang H, Zhao Y

Adv Healthc Mater 12 (24) e2300673 [2023-09-00; online 2023-05-14]

Super-resolution proximity labeling reveals anti-viral protein network and its structural changes against SARS-CoV-2 viral proteins.

Lee Y, Jung M, Kim J, ..., Mun JY, Rhee H

Cell Rep 42 (8) 112835 [2023-08-29; online 2023-07-20]

Prognostic potential of creatinine and Cystatin C in COVID-19 - a retrospective cohort study from Karolinska University Hospital.

Sjöström A, Markgren PO, Hansson M

Scand J Clin Lab Invest 83 (4) 251-257 [2023-07-00; online 2023-05-11]

Category: Proteins Category: Serology Type: Journal article

Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis.

Abdelhak A, Barba L, Romoli M, ..., Foschi M, Abu-Rumeileh S

J Neurol 270 (7) 3315-3328 [2023-07-00; online 2023-05-15]

Category: Health Category: Proteins Type: Journal article

Reduced Binding between Omicron B.1.1.529 and the Human ACE2 Receptor in a Surrogate Virus Neutralization Test for SARS-CoV-2.

Hoffman T, Kolstad L, Akaberi D, ..., Rönnberg B, Lundkvist Å

Viruses 15 (6) - [2023-05-30; online 2023-05-30]

Category: Proteins Category: Serology Funder: KAW/SciLifeLab National COVID program Funder: VR Type: Journal article

Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion.

Eser TM, Baranov O, Huth M, ..., Hoelscher M, Geldmacher C

Nat Commun 14 (1) 2952 [2023-05-24; online 2023-05-24]

Category: Biochemistry Category: Proteins Type: Journal article

Long COVID is primarily a Spike protein Induced Thrombotic Vasculitis

Kerr R, Carroll HA

- - (-) - [2023-05-18; online 2023-05-18]

Category: Post-COVID Category: Proteins Type: Preprint

A novel precision-serology assay for SARS-CoV-2 infection based on linear B-cell epitopes of Spike protein.

Lundin SB, Kann H, Fulurija A, ..., Gisslén M, Harandi AM

Front Immunol 14 (-) 1166924 [2023-05-12; online 2023-05-12]

Category: Proteins Category: Serology Funder: KAW/SciLifeLab National COVID program Funder: VR Funder: Vinnova Type: Journal article

Seroprevalence and T-cell response in 32 children 10 months after COVID-19.

Moritz D, Krifors A, Freyhult E, Månsson E

Acta Paediatr - (-) - [2022-02-12; online 2022-02-12]

Category: Health Category: Proteins Type: Journal article

The effects of a physical and cognitive training intervention vs. physical training alone on older adults' physical activity: A randomized controlled trial with extended follow-up during COVID-19.

Savikangas T, Törmäkangas T, Tirkkonen A, ..., Stigsdotter Neely A, Sipilä S

PLoS One 16 (10) e0258559 [2021-10-13; online 2021-10-13]

Dynamic Interactions of Fully Glycosylated SARS-CoV-2 Spike Protein with Various Antibodies.

Cao Y, Choi YK, Frank M, ..., Seok C, Im W

J Chem Theory Comput 17 (10) 6559-6569 [2021-10-12; online 2021-09-16]

Category: Drug Discovery Category: Health Category: Proteins Type: Journal article

Association Between Risk of COVID-19 Infection in Nonimmune Individuals and COVID-19 Immunity in Their Family Members.

Nordström P, Ballin M, Nordström A

JAMA Intern Med - (-) - [2021-10-11; online 2021-10-11] Open Access

Antiphospholipid antibodies and neurological manifestations in acute COVID-19: A single-centre cross-sectional study.

Benjamin LA, Paterson RW, Moll R, ..., Efthymiou M, UCLH Queen Square COVID-19 Biomarker Study group

EClinicalMedicine 39 (-) 101070 [2021-09-00; online 2021-08-12] Open Access

Category: Biochemistry Category: Health Category: Proteins Type: Journal article

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

Asano T, Boisson B, Onodi F, ..., Zhang Q, Casanova JL

Sci Immunol 6 (62) eabl4348 [2021-08-19; online 2021-08-21]

Category: Biochemistry Category: Health Category: Proteins Type: Journal article

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.

Bastard P, Gervais A, Le Voyer T, ..., Abel L, Casanova JL

Sci Immunol 6 (62) eabl4340 [2021-08-19; online 2021-08-21] Open Access

Category: Biochemistry Category: Health Category: Proteins Type: Journal article

Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1.

Bastard P, Orlova E, Sozaeva L, ..., Casanova JL, Lionakis MS

J Exp Med 218 (7) - [2021-07-05; online 2021-04-24]

Category: Biochemistry Category: Health Category: Proteins Type: Journal article

Rapid diagnostic testing for SARS-CoV-2: Validation and comparison of three point-of-care antibody tests.

Strand R, Thelaus L, Fernström N, ..., Linder A, Rasmussen M

J Med Virol 93 (7) 4592-4596 [2021-07-00; online 2021-05-03]

Category: Health Category: Other Category: Proteins Type: Journal article

SARS-CoV-2 antigen testing: weighing the false positives against the costs of failing to control transmission.

Fearon E, Buchan IE, Das R, ..., Stage HB, Wingfield T

Lancet Respir Med - (-) - [2021-06-14; online 2021-06-14]

Category: Biochemistry Category: Health Category: Proteins Type: Journal article

High-throughput immunoassays for SARS-CoV-2 - considerable differences in performance when comparing three methods.

Ekelund O, Ekblom K, Somajo S, ..., Olsson K, Petersson A

Infect Dis (Lond) - (-) 1-6 [2021-05-29; online 2021-05-29]

Category: Biochemistry Category: Proteins Type: Journal article

Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane.

Choi YK, Cao Y, Frank M, ..., Seok C, Im W

J Chem Theory Comput 17 (4) 2479-2487 [2021-04-13; online 2021-03-10]

Category: Biochemistry Category: Proteins Type: Journal article

Ultra-fast proteomics with Scanning SWATH.

Messner CB, Demichev V, Bloomfield N, ..., Tate S, Ralser M

Nat Biotechnol - (-) - [2021-03-25; online 2021-03-25]

Category: Biochemistry Category: Proteins Type: Journal article

Anti-SARS-CoV2 antibody responses in serum and cerebrospinal fluid of COVID-19 patients with neurological symptoms

Cunningham JL, Virhammar J, Rönnberg B, ..., Karlsson Hedestam GB, Rostami E

The Journal of Infectious Diseases - (-) - [2021-03-21; online 2021-03-21] Open Access

Category: Biochemistry Category: Health Category: Proteins Funder: H2020 Funder: KAW/SciLifeLab National COVID program Funder: VR Research Area: High-throughput and high-content serology Type: Journal article

COVID-19 Antibody Testing of Patients Admitted to the ICU by a Novel, Point-of-Care Assay, and the Relationship to Survival

Casswell S, Eriksson AK, Moberg L, ..., Marshall F, Venge P

Research Square - (-) - [2021-03-10; online 2021-03-10]

Category: Biochemistry Category: Proteins Funder: KAW/SciLifeLab National COVID program Research Area: Biobanks for COVID-19 research Type: Preprint

Antibodies to SARS-CoV-2 and risk of past or future sick leave.

Dillner J, Elfström KM, Blomqvist J, ..., Mühr LSA, Conneryd Lundgren K

Sci Rep 11 (1) 5160 [2021-03-04; online 2021-03-04] Open Access

Category: Health Category: Proteins Funder: KAW/SciLifeLab National COVID program Research Area: High-throughput and high-content serology Type: Journal article

Protection induced by a human monoclonal antibody recognizing two different epitopes in a conserved region of streptococcal M proteins

Bahnan W, Happonen L, Khakzad H, ..., Malmström J, Nordenfelt P

bioRxiv - (-) - [2021-03-02; online 2021-03-02]

Category: Biochemistry Category: Proteins Type: Preprint

Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection.

Manisty C, Treibel TA, Jensen M, ..., Noursadeghi M, Moon JC

EBioMedicine 65 (-) 103259 [2021-03-01; online 2021-03-01]

Category: Genomics & transcriptomics Category: Proteins Funder: H2020 Type: Journal article

Functional myeloid-derived suppressor cells expand in blood but not airways of COVID-19 patients and predict disease severity

Falck-Jones S, Vangeti S, Yu M, ..., Farnert A, Smed-Sorensen A

J Clin Invest 131 (6) - [2021-01-28; online 2021-01-25] Open Access

Category: Health Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Research Area: High-throughput and high-content serology Type: Journal article

Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease

De Gasparo R, Pedotti M, Simonelli L, ..., Ruzek D, Varani L

- - (-) - [2021-01-22; online 2021-01-22]

Category: Biochemistry Category: Proteins Type: Preprint

Psychological Impact of COVID-19 Cases on Medical Staff of Beijing Xiaotangshan Hospital.

Fu Y, Wang M, Zhao B, ..., Li B, Liu Q

Psychol Res Behav Manag 14 (-) 41-47 [2021-01-18; online 2021-01-18]

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

Koenig PA, Das H, Liu H, ..., Wu NC, Schmidt FI

Science 371 (6530) eabe6230 [2021-01-12; online 2021-01-12]

Category: Biochemistry Category: Imaging Category: Proteins Funder: H2020 Funder: VR Type: Journal article

Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs.

Moliner-Morro A, J Sheward D, Karl V, ..., McInerney GM, Hanke L

Biomolecules 10 (12) - [2020-12-11; online 2020-12-11]

Category: Biochemistry Category: Proteins Funder: H2020 Funder: VR Funder: VR: Special COVID-19 funding Type: Journal article

Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses

Tampere M, Pettke A, Salata C, ..., Jafari R, Puumalainen MR

Viruses 12 (12) 1423 [2020-12-10; online 2020-12-10]

Category: Biochemistry Category: Drug Discovery Category: Genomics & transcriptomics Category: Proteins Funder: VR Type: Journal article

The Structural Basis of Accelerated Host Cell Entry by SARS-CoV-2 †.

Seyran M, Takayama K, Uversky VN, ..., Brufsky AM, Uhal BD

FEBS J - (-) - [2020-12-02; online 2020-12-02]

Category: Biochemistry Category: Proteins Type: Journal article

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2

Custódio TF, Das H, Sheward DJ, ..., Hällberg BM, Löw C

Nat Commun 11 (1) - [2020-11-04; online 2020-11-04] Open Access

Category: Biochemistry Category: Other Category: Proteins Funder: H2020 Funder: KAW/SciLifeLab National COVID program Funder: VR Research Area: Host cell systems biology and targets Type: Journal article

Expansion of SARS-CoV-2-Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients.

Varnaitė R, García M, Glans H, ..., Klingström J, Gredmark-Russ S

J Immunol 205 (9) 2437-2446 [2020-11-01; online 2020-09-02]

Category: Biochemistry Category: Health Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Research Area: Host cell systems biology and targets Type: Journal article

Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2.

Rogstam A, Nyblom M, Christensen S, ..., Knecht W, Kozielski F

Int J Mol Sci 21 (19) - [2020-10-06; online 2020-10-06]

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.

Sekine T, Perez-Potti A, Rivera-Ballesteros O, ..., Aleman S, Buggert M

Cell 183 (1) 158-168.e14 [2020-10-01; online 2020-08-14] Open Access

Category: Genomics & transcriptomics Category: Other Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Research Area: Data-driven research – models and AI Research Area: Host cell systems biology and targets Type: Journal article

MAIT cell activation and dynamics associated with COVID-19 disease severity.

Parrot T, Gorin J, Ponzetta A, ..., Strålin K, Sandberg JK

Sci Immunol 5 (51) - [2020-09-28; online 2020-09-30]

Category: Genomics & transcriptomics Category: Health Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Research Area: Data-driven research – models and AI Research Area: Host cell systems biology and targets Type: Journal article

Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro

Akaberi D, Krambrich J, Ling J, ..., Lennerstrand J, Lundkvist Å

Redox Biology 37 (-) 101734 [2020-09-21; online 2020-09-21] Open Access

Category: Imaging Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Research Area: Drug discovery and repurposing of drugs Type: Journal article

Development, clinical translation, and utility of a COVID-19 antibody test with qualitative and quantitative readouts.

Bortz RH, Florez C, Laudermilch E, ..., Lai JR, Chandran K

mSphere 6 (2) - [2020-09-11; online 2020-09-11]

Category: Biochemistry Category: Health Category: Proteins Category: Serology Type: Journal article

Natural killer cell immunotypes related to COVID-19 disease severity.

Maucourant C, Filipovic I, Ponzetta A, ..., Björkström NK, Karolinska COVID-19 Study Group

Sci Immunol 5 (50) - [2020-08-21; online 2020-08-23]

Category: Biochemistry Category: Genomics & transcriptomics Category: Health Category: Imaging Category: Other Category: Proteins Funder: KAW/SciLifeLab National COVID program Funder: VR Funder: VR: Special COVID-19 funding Research Area: Data-driven research – models and AI Research Area: Diagnostics for virus Research Area: Host cell systems biology and targets Type: Journal article

On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2.

Corrêa Giron C, Laaksonen A, Barroso da Silva FL

Virus Res 285 (-) 198021 [2020-08-00; online 2020-05-15]

Category: Biochemistry Category: Proteins Type: Journal article

Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection.

Messner CB, Demichev V, Wendisch D, ..., Sander LE, Ralser M

Cell Syst 11 (1) 11-24.e4 [2020-07-22; online 2020-06-02]

Category: Other Category: Proteins Category: Serology Type: Journal article