Research Area: Host cell systems biology and targets

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Primary: Shown in the list of current labels.

Year 2022

PubMed DOI Crossref
SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection
Havervall S, Jernbom Falk A, Klingström J, ..., Nilsson P, Thålin C
PLoS One 17 (1) e0262169 [2022-01-12; online 2022-01-12]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Funder: VR Research Area: Biobanks for COVID-19 research Research Area: Drug discovery and repurposing of drugs Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19.
Havervall S, Ng H, Jernbom Falk A, ..., Hober S, Thålin C
J Intern Med 291 (1) 72-80 [2022-01-00; online 2021-09-27]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: Drug discovery and repurposing of drugs Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Research Area: Viral sequence evolution

Year 2021

DOI Crossref
Clinical grade ACE2 effectively inhibits SARS-CoV-2 Omicron infections
Monteil V, Stephanie D, Klingström J, ..., Penninger JM, Mirazimi A
bioRxiv - (-) - [2021-12-27; online 2021-12-27]
Category: Biochemistry Category: Health Category: Omicron VoC Funder: KAW/SciLifeLab Research Area: Host cell systems biology and targets Type: Preprint
PubMed DOI Crossref
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2
Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM
Nat Commun 12 (1) - [2021-12-00; online 2021-06-17]
Category: Health Category: Serology Funder: H2020 Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Kruse T, Benz C, Garvanska DH, ..., Nilsson J, Ivarsson Y
Nat Commun 12 (1) 6761 [2021-11-19; online 2021-11-19]
Category: Biochemistry Category: Drug Discovery Category: Health Funder: KAW/SciLifeLab Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Longitudinal Follow Up of Immune Responses to SARS-CoV-2 in Health Care Workers in Sweden With Several Different Commercial IgG-Assays, Measurement of Neutralizing Antibodies and CD4+ T-Cell Responses.
Marklund E, Leach S, Nyström K, ..., Bemark M, Gisslén M
Front Immunol 12 (-) 750448 [2021-11-02; online 2021-11-02]
Category: Biochemistry Category: Health Funder: Hjärt-Lungfonden Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: Host cell systems biology and targets Research Area: Vaccine Type: Journal article
PubMed DOI Crossref
A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies.
Mravinacova S, Jönsson M, Christ W, ..., Månberg A, Hober S
N Biotechnol 66 (-) 46-52 [2021-10-07; online 2021-10-07]
Category: Biochemistry Category: Health Funder: H2020 Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
DOI Crossref
Neutralization of VOCs including Delta one year post COVID-19 or vaccine
Havervall S, Marking U, Gordon M, ..., Hober S, Thålin C
MedRxiv - (-) - [2021-08-12; online 2021-08-12]
Category: Biochemistry Category: Health Category: Vaccines Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: Drug discovery and repurposing of drugs Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Preprint
PubMed DOI Crossref
Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2
Havervall S, Marking U, Greilert-Norin N, ..., Åberg M, Thålin C
EBioMedicine 70 (-) 103523 [2021-08-00; online 2021-08-00]
Category: Drug Discovery Category: Health Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: Drug discovery and repurposing of drugs Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.
Hober S, Hellström C, Olofsson J, ..., Hedhammar M, Nilsson P
Clin Transl Immunol 10 (7) e1312 [2021-07-19; online 2021-07-19]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Research Area: Biobanks for COVID-19 research Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation.
Sandberg JT, Varnaitė R, Christ W, ..., Gredmark-Russ S, Karolinska COVID‐19 Study Group
Clin Transl Immunol 10 (7) e1306 [2021-07-05; online 2021-07-05]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Cytoplasmic short linear motifs in ACE2 and integrin β3 link SARS-CoV-2 host cell receptors to endocytosis and autophagy
Kliche J, Ali M, Ivarsson Y
Sci Signal 14 (665) - [2021-01-12; online 2020-10-06]
Category: Biochemistry Funder: VR Research Area: Host cell systems biology and targets Type: Journal article

Year 2020

PubMed DOI Crossref
Perturbations in the mononuclear phagocyte landscape associated with COVID-19 disease severity
Kvedaraite E, Hertwig L, Indranil S, ..., Henter J, Svensson M
Proc Natl Acad Sci U S A 118 (6) - [2020-11-17; online 2021-01-23]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Funder: VR Funder: Vinnova Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.
Stebbing J, Sánchez Nievas G, Falcone M, ..., Abizanda P, Lauschke VM
Sci Adv 7 (1) - [2020-11-13; online 2020-11-13]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Funder: VR Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Custódio TF, Das H, Sheward DJ, ..., Hällberg BM, Löw C
Nat Commun 11 (1) - [2020-11-04; online 2020-11-04]
Category: Biochemistry Category: Other Category: Proteins Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Innate lymphoid cell composition associates with COVID-19 disease severity
García M, Kokkinou E, Carrasco García A, ..., Mjösberg J, Group tKKCS
Clin Transl Immunol 9 (12) - [2020-11-04; online 2020-10-14]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Funder: VR Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Expansion of SARS-CoV-2–Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients
Varnaite R, García M, Glans H, ..., Klingström J, Gredmark-Russ S
The Journal of Immunology 205 (5) - [2020-11-01; online 2020-10-19]
Category: Biochemistry Category: Health Category: Proteins Funder: KAW/SciLifeLab Funder: VR Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden.
Rudberg A, Havervall S, Månberg A, ..., Hober S, Thålin C
Nat Commun 11 (1) 5064 [2020-10-08; online 2020-10-08]
Category: Health Category: Serology Funder: H2020 Funder: KAW/SciLifeLab Funder: VR Research Area: Biobanks for COVID-19 research Research Area: High-throughput and high-content serology Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Sekine T, Perez-Potti A, Rivera-Ballesteros O, ..., Aleman S, Buggert M
Cell 183 (1) 158-168.e14 [2020-10-01; online 2020-08-14]
Category: Genomics & transcriptomics Category: Other Category: Proteins Funder: KAW/SciLifeLab Funder: VR Research Area: Data-driven research – models and AI Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
MAIT cell activation and dynamics associated with COVID-19 disease severity.
Parrot T, Gorin J, Ponzetta A, ..., Strålin K, Sandberg JK
Sci Immunol 5 (51) - [2020-09-28; online 2020-09-30]
Category: Genomics & transcriptomics Category: Health Category: Proteins Funder: KAW/SciLifeLab Funder: VR Research Area: Data-driven research – models and AI Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Psychological impact of COVID-19 in the Swedish population: Depression, anxiety, and insomnia and their associations to risk and vulnerability factors.
McCracken LM, Badinlou F, Buhrman M, Brocki KC
Eur Psychiatry 63 (1) e81 [2020-08-26; online 2020-08-26]
Category: Health Category: Social Science & Humanities Funder: VR Research Area: Host cell systems biology and targets Type: Journal article
PubMed DOI Crossref
Natural killer cell immunotypes related to COVID-19 disease severity.
Maucourant C, Filipovic I, Ponzetta A, ..., Björkström NK, Karolinska COVID-19 Study Group
Sci Immunol 5 (50) - [2020-08-21; online 2020-08-23]
Category: Biochemistry Category: Genomics & transcriptomics Category: Health Category: Imaging Category: Other Category: Proteins Funder: KAW/SciLifeLab Funder: VR Funder: VR: Special COVID-19 funding Research Area: Data-driven research – models and AI Research Area: Diagnostics for virus Research Area: Host cell systems biology and targets Type: Journal article
DOI Crossref
Effect of statins on SARS-CoV-2 infection
Moeller R, Zapatero-Belinchón FJ, Lasswitz L, ..., Kluge S, Gerold G
medRxiv - (-) - [2020-07-14; online 2020-07-14]
Category: Health Funder: KAW/SciLifeLab Research Area: Host cell systems biology and targets Type: Preprint
PubMed DOI Crossref
Detection of asymptomatic SARS-CoV-2 exposed individuals by a sensitive S-based ELISA
Rosendal E, Byström JW, Gröning R, ..., Överby AK, Forsell MN
medRxiv - (-) - [2020-06-04; online 2020-06-04]
Category: Biochemistry Category: Health Funder: KAW/SciLifeLab Funder: VR Funder: Vinnova Research Area: Biobanks for COVID-19 research Research Area: Host cell systems biology and targets Type: Preprint

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Publications 8.1.1